Active Ingredients Monomer suppliers Introduction Pure Ferulic Acid Powder is a kind of phenolic acid extracted from the resin of ferulic acid. Ferulic acid is a perennial herb of Umbelliferae with a strong garlic odor. It is born in sandy areas, mainly in Xinjiang. Flower stems are drawn from the fifth year. The flower stem is stout, up to 2 meters high; from the flowering stage to the early fruit stage in late spring and early summer, cut the obliquely from the upper part of the stem to the bottom, collect the exuded milky resin, and dry it in the shade. Ferulic acid contains volatile oil, resin and gum, etc. The oil contains various organic acid compounds, such as (R)-sec-butyl 1-propenyl disulfide, 1(1-methylthiopropyl) 1-propenyl disulfide Thioether, sec-butyl 3-methylthioallyl disulfide, etc. The resin contains ferulic acid and its esters. As a phenolic plant component, ferulic acid has strong antioxidant activity and has a great effect on human health. Ferulic acid can significantly increase the content of glutathione and nicotinamide adenine dinucleotide phosphate in irradiated cells, and has a protective effect on irradiated endothelial cells. Heme oxygenase is an antioxidant enzyme that converts heme into biliverdin and finally into the antioxidant bilirubin. Ferulic acid can well regulate the expression of this enzyme , so as to play a protective role in radiation protection Certificate of Analysis ItemSpecificationTest result AssayFerulic Acid鈮?8.0%98.08% HPLC Physical Control AppearanceWhite or off-white PowderComplies OdorCharacteristicComplies TasteCharacteristicComplies Part UsedRice branComplies Loss on Drying鈮?.50%0.35% Ash鈮?.0%0.10% Particle size95% pass 80 meshComplies AllergensNoneComplies Chemical Control Heavy metals鈮?0ppmComplies Arsenic (As)鈮?ppmComplies Mercury(Hg)鈮?.1ppmComplies Lead (Pb)鈮?ppmComplies Cadmium(Cd)鈮?ppmComplies GMO StatusGMO FreeComplies Microbiological Control Total Plate Count鈮?,000cfu/gComplies Yeast & Mold鈮?00cfu/gComplies ColiformsNegativeNegative E.ColiNegativeNegative Salmonella sp.NegativeNegative Pure Ferulic Acid Powder Flow Chart Function 1. Anti-radiation effect Radiation-induced organ failure is largely caused by chronic peroxidative damage. The damage caused by radiation to the body can be divided into two types: direct damage and indirect damage. Direct damage means that radiation directly causes the rupture of some sensitive molecules in the cell; indirect damage is the radiolysis of water, which leads to the increase of intracellular reactive oxygen species and the subcellular structure. Therefore, antioxidants are widely used in the treatment of radiation damage. Protection of cells from reactive oxygen species damage must maintain the homeostasis of the endogenous thiol pool, especially glutathione (GSH) and nicotinamide adenine dinucleotide phosphate (NADPH) levels. Glutathione provides reducing equivalents for the conversion of hydrogen peroxide and lipid peroxides to water and lipid alcohols, protecting sulfhydryl protein groups from oxidative damage. The rate-limiting reaction of glutathione biosynthesis is catalyzed by glutamate-cysteine ligase (GCL), which consists of a catalytic subunit (GCLC) and a regulatory subunit (GCLM). . Nicotinamide adenine dinucleotide phosphate is an important antioxidant component in tissues, which can maintain the redox potential of cells by reducing the reducing equivalents of glutathione reductase and thioredoxin. 2. Antioxidant function Metabolism is a characteristic of living organisms, and living organisms are constantly being affected by reactive oxygen species (molecules or free radicals that are directly or indirectly transformed from molecular oxygen and are more active than molecular oxygen), free radicals (also known as free radicals, It refers to the attack of atoms, atomic groups or molecules with special states that contain unpaired electrons in the outer orbits. Both of these substances can directly participate in the formation of tumors or induce the production of carcinogens, resulting in changes in the DNA of living organisms and proto-oncogenes. It is a key link in the prevention and treatment of related diseases to promote the body to produce cells and reduce antioxidant damage. Some studies have shown that ferulic acid can quench free radicals and restore the normal function of the living body. Ferulic acid can inhibit the enzymes that produce free radicals in the living body. On this basis, it can also increase the enzymes that scavenge free radicals. At the same time, ferulic acid can greatly enhance the activity of aldehyde reductase and glutathione transsulfurase, and control the proportion of active tyrosinase. Studies have shown that ferulic acid has a significant antioxidant effect, and has a good scavenging effect on ammonia peroxide, superoxide radicals, hydroxyl radicals, and nitroperoxides. 3. Antibacterial and antiviral functions The study found that after the macrophages of the experimental mice were infected with influenza virus, a blank control was set without treatment, and the experimental group was treated with ferulic acid and isoferulic acid. Analysis of the results showed that the production of interferon in the experimental group decreased rapidly. In recent years, there have been many reports that ferulic acid has significant inhibitory effects on cold virus (IV), respiratory syncytial virus (RSV) and HIV (HIV), and the effect of ferulic acid on inflammatory proteins was studied in the same cell line. As a result, ferulic acid can sharply reduce the production of this protein. Among them, ferulic acid has an inhibitory effect on HIV, so there is a possibility that ferulic acid will become a future chemotherapeutic agent. It is speculated that the inhibitory mechanism of ferulic acid on viruses is related to its ability to reduce the activity of xanthine oxidase, because such enzymes can generally lead to some inflammations. The N-acetyltransferase has a strong inhibitory effect Application 1. In addition to being widely used in medicine, ferulic acid has been approved as a food additive in some countries. Japan has allowed the use of food antioxidants, and the United States and some European countries have allowed the use of some herbs, coffee, vanilla beans, etc., containing high ferulic acid as antioxidants. Ferulic acid is mainly used in the food industry to prepare natural vanillin, antioxidants, preservatives, cross-linking agents and functional accelerators. 2. Ferulic acid has the functions of inhibiting platelet aggregation, expectorant, and inhibiting Mycobacterium tuberculosis. Clinically, ferulic acid is mainly used for the adjuvant treatment of vascular diseases such as arteriosclerosis, coronary heart disease, cerebrovascular disease, glomerular disease, pulmonary hypertension, diabetic vascular disease, vasculitis, and leukopenia and thrombocytopenia. It can be used for the treatment of migraine and vascular headache. As a leukocyte-increasing drug, this drug also has the effect of enhancing hematopoietic function. Therefore, ferulic acid can also be used for the treatment of white blood cells and thrombocytopenia. 3. Pure Ferulic acid Powder is easily metabolized by the human body and can be used as a food preservative. It is widely used in food, medicine, etc. It inhibits the synthesis of cholesterol in the liver, thereby achieving the purpose of lowering blood lipids, and has a broader inhibitory effect on bacteria. In addition to being widely used in medicine, some countries have approved it as a food additive. 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